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Sildenafil can be a strong and selective inhibitor of cGMP-precise phosphodiesterase kind 5 (PDE5), which is chargeable for degradation of cGMP inside the corpus cavernosum. The molecular composition of sildenafil is comparable to that of cGMP and functions like a competitive binding agent of PDE5 while in the corpus cavernosum, leading to more cGM

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